Statements (92)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:complex
|
gptkbp:associated_with |
interferon signaling
|
gptkbp:has_component |
gptkb:OAS1
OAS2 OAS3 |
gptkbp:has_role |
immune response
cellular signaling |
https://www.w3.org/2000/01/rdf-schema#label |
OAS complex
|
gptkbp:initiated_by |
viral infections
viral proteins double-stranded RNA viral RNA immune challenges immune stimuli pathogen recognition receptors pathogen-associated molecular patterns |
gptkbp:interacts_with |
gptkb:RNase_L
|
gptkbp:investigates |
gptkb:gene_therapy
biomarker discovery therapeutic interventions therapeutic strategies therapeutic applications novel treatments |
gptkbp:involved_in |
RNA degradation
antiviral response |
gptkbp:is_affected_by |
pathogen evasion strategies
|
gptkbp:is_associated_with |
inflammatory responses
chronic inflammation chronic inflammatory diseases chronic viral infections systemic diseases chronic inflammation syndromes metabolic syndromes |
gptkbp:is_characterized_by |
enzyme activity
|
gptkbp:is_essential_for |
host defense
|
gptkbp:is_expressed_in |
gptkb:Cell
brain tissue inflammatory responses viral infections respiratory tract liver cells immune activation immune tissues |
gptkbp:is_found_in |
cytoplasm
|
gptkbp:is_involved_in |
cellular homeostasis
cellular stress response cellular differentiation cellular signaling pathways host-pathogen interactions cellular repair mechanisms cellular signaling cascades viral pathogenesis cellular stress responses cellular immunity cellular apoptosis cellular signaling pathways. m RNA surveillance protein synthesis inhibition |
gptkbp:is_linked_to |
gptkb:chronic_fatigue_syndrome
gptkb:neurodegenerative_diseases metabolic disorders autoimmune diseases chronic diseases tumor progression autoimmune disorders chronic infections |
gptkbp:is_part_of |
signal transduction pathways
innate immune system immune response pathways antiviral pathways cellular defense systems immune surveillance mechanisms viral defense mechanisms |
gptkbp:is_regulated_by |
cytokines
|
gptkbp:is_related_to |
apoptosis
|
gptkbp:is_studied_for |
preventive measures
vaccine development clinical applications diagnostic markers |
gptkbp:is_studied_in |
clinical trials
cancer research infectious diseases |
gptkbp:is_targeted_at |
therapeutic agents
small molecules antiviral drugs biological therapies immune modulators therapeutic compounds |
gptkbp:produces |
2',5'-oligoadenylates
|
gptkbp:regulates |
viral replication
|
gptkbp:bfsParent |
gptkb:Pan-American_Union_Building
|
gptkbp:bfsLayer |
7
|