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gptkbp:instanceOf
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gptkb:protein
gptkb:enzyme
|
|
gptkbp:catalyzes
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transcription of DNA to synthesize RNA
|
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gptkbp:component
|
gptkb:nucleus
nucleoplasm
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gptkbp:discoveredBy
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gptkb:Robert_Roeder
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gptkbp:discoveredIn
|
1969
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gptkbp:EC_number
|
2.7.7.6
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gptkbp:encodedBy
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gptkb:POLR1C_gene
gptkb:POLR2A_gene
gptkb:POLR2B_gene
gptkb:POLR2C_gene
gptkb:POLR2D_gene
gptkb:POLR2E_gene
gptkb:POLR2F_gene
gptkb:POLR2G_gene
gptkb:POLR2H_gene
gptkb:POLR2I_gene
gptkb:POLR2J_gene
gptkb:POLR2K_gene
gptkb:POLR2L_gene
gptkb:POLR2M_gene
gptkb:POLR2N_gene
gptkb:POLR2O_gene
gptkb:POLR2P_gene
gptkb:POLR2Q_gene
gptkb:POLR2R_gene
gptkb:POLR2S_gene
gptkb:POLR2T_gene
gptkb:POLR2U_gene
gptkb:POLR2V_gene
gptkb:POLR2W_gene
gptkb:POLR2X_gene
gptkb:POLR2Y_gene
gptkb:POLR2Z_gene
gptkb:POLR3A_gene
gptkb:POLR3B_gene
gptkb:POLR3C_gene
gptkb:POLR3D_gene
gptkb:POLR3E_gene
gptkb:POLR3F_gene
gptkb:POLR3GL_gene
gptkb:POLR3G_gene
gptkb:POLR3H_gene
gptkb:POLR3K_gene
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gptkbp:foundIn
|
eukaryotic cells
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gptkbp:function
|
DNA-directed 5'-3' RNA polymerase activity
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gptkbp:GOProcess
|
transcription by RNA polymerase III
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|
https://www.w3.org/2000/01/rdf-schema#label
|
RNA polymerase III
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gptkbp:inhibitedBy
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gptkb:ML-60218
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gptkbp:involvedIn
|
cell proliferation
cell growth
response to stress
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gptkbp:largestSubunit
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gptkb:POLR3A
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gptkbp:mutationAssociatedWith
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gptkb:Treacher_Collins_syndrome
gptkb:hypomyelinating_leukodystrophy
gptkb:Wiedemann-Rautenstrauch_syndrome
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gptkbp:relatedTo
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gptkb:RNA_polymerase_I
gptkb:RNA_polymerase_II
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gptkbp:requires
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gptkb:TFIIIA_(for_5S_rRNA_genes)
gptkb:TFIIIC
gptkb:TFIIIB
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gptkbp:secondLargestSubunit
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gptkb:POLR3B
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gptkbp:sensitivity
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α-amanitin (at high concentrations)
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gptkbp:subunit
|
17 subunits in humans
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gptkbp:transcribes
|
gptkb:5S_rRNA_genes
tRNA genes
other small RNAs
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gptkbp:UniProtID
|
gptkb:P05423_(POLR3A)
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gptkbp:bfsParent
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gptkb:gene
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gptkbp:bfsLayer
|
5
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