Statements (25)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
Recombination activating gene 1 protein
|
gptkbp:associatedWith |
immune system
|
gptkbp:discoveredIn |
1990
|
gptkbp:encodedBy |
gptkb:RAG1_gene
|
gptkbp:formsComplexWith |
gptkb:RAG-2_protein
|
gptkbp:foundIn |
gptkb:Homo_sapiens
|
gptkbp:function |
gptkb:V(D)J_recombination
DNA cleavage |
https://www.w3.org/2000/01/rdf-schema#label |
RAG-1 protein
|
gptkbp:locatedOnChromosome |
chromosome 11p13
|
gptkbp:location |
gptkb:nucleus
|
gptkbp:molecularWeight |
~120 kDa
|
gptkbp:mutationAssociatedWith |
gptkb:Omenn_syndrome
immunodeficiency |
gptkbp:presentIn |
vertebrates
|
gptkbp:requires |
immunoglobulin gene rearrangement
lymphocyte development T cell receptor gene rearrangement |
gptkbp:structure |
contains zinc finger domain
|
gptkbp:UniProtID |
P15918
|
gptkbp:bfsParent |
gptkb:RAG-2_protein
gptkb:Rag1 gptkb:RAG2_gene |
gptkbp:bfsLayer |
8
|