Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
membrane trafficking
|
| gptkbp:discoveredBy |
1980s
|
| gptkbp:dysregulationAssociatedWith |
diseases such as cancer and neurological disorders
|
| gptkbp:encodes |
Rab proteins
|
| gptkbp:example |
gptkb:RAB5
RAB1 RAB11 RAB7 RAB10 RAB14 RAB27 RAB3 RAB35 RAB8 |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
regulation of vesicle trafficking
|
| https://www.w3.org/2000/01/rdf-schema#label |
RAB genes
|
| gptkbp:interactsWith |
effector proteins
|
| gptkbp:involves |
endocytosis
exocytosis |
| gptkbp:localizes_to |
specific intracellular membranes
|
| gptkbp:member |
gptkb:Ras_superfamily
|
| gptkbp:number_of_members_in_humans |
over 60
|
| gptkbp:orthologIn |
gptkb:yeast
animals plants |
| gptkbp:regulates |
GTP binding and hydrolysis
|
| gptkbp:bfsParent |
gptkb:Rab_protein
|
| gptkbp:bfsLayer |
6
|