Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:allostericallyRegulatedBy |
gptkb:fructose_1,6-bisphosphate
|
| gptkbp:alternativeName |
gptkb:PKM2
Cytosolic pyruvate kinase |
| gptkbp:alternativeSplicing |
gptkb:PKM1
|
| gptkbp:catalyzes |
conversion of phosphoenolpyruvate to pyruvate
|
| gptkbp:EC_number |
2.7.1.40
|
| gptkbp:encodedBy |
gptkb:PKM_gene
|
| gptkbp:expressedIn |
cancer cells
proliferating cells |
| gptkbp:foundIn |
gptkb:human
other mammals |
| https://www.w3.org/2000/01/rdf-schema#label |
Pyruvate kinase M2
|
| gptkbp:inhibitedBy |
phosphotyrosine proteins
|
| gptkbp:involvedIn |
gptkb:Warburg_effect
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_15
|
| gptkbp:molecularWeight |
~58 kDa
|
| gptkbp:PDB |
3BJF
|
| gptkbp:produces |
gptkb:ATP
|
| gptkbp:regulates |
glycolysis
|
| gptkbp:structure |
dimer
tetramer |
| gptkbp:UniProtID |
P14618
|
| gptkbp:usedAs |
biomarker
|
| gptkbp:bfsParent |
gptkb:PKM2
|
| gptkbp:bfsLayer |
7
|