Statements (17)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological sequence motif
|
| gptkbp:abbreviation |
gptkb:PAM
|
| gptkbp:discoveredIn |
gptkb:Bacteria
archaea |
| gptkbp:firstDescribed |
2005
|
| gptkbp:foundIn |
CRISPR systems
|
| gptkbp:function |
enables discrimination between self and non-self DNA
|
| https://www.w3.org/2000/01/rdf-schema#label |
Protospacer Adjacent Motif
|
| gptkbp:recognizedBy |
gptkb:Cas_proteins
|
| gptkbp:requires |
CRISPR-Cas targeting
|
| gptkbp:role |
genome editing
adaptive immunity in prokaryotes |
| gptkbp:sequence |
NGG (for SpCas9)
TTTV (for Cpf1/Cas12a) short DNA sequence |
| gptkbp:bfsParent |
gptkb:PAM
|
| gptkbp:bfsLayer |
7
|