Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:software
|
| gptkbp:citation |
Adzhubei IA, et al. Nat Methods. 2010
|
| gptkbp:developer |
Bork Group
Sunyaev Lab |
| gptkbp:firstReleased |
2002
|
| gptkbp:fullName |
Polymorphism Phenotyping
|
| https://www.w3.org/2000/01/rdf-schema#label |
PolyPhen
|
| gptkbp:input |
gptkb:protein
amino acid substitution |
| gptkbp:latestReleaseVersion |
gptkb:PolyPhen-2
|
| gptkbp:output |
probability score
prediction of damaging effect |
| gptkbp:purpose |
predicts possible impact of amino acid substitutions on protein structure and function
|
| gptkbp:relatedTo |
gptkb:SIFT
gptkb:MutationTaster PROVEAN |
| gptkbp:supportsAlgorithm |
gptkb:machine_learning
sequence-based structure-based |
| gptkbp:usedIn |
clinical genomics
genetic variant interpretation |
| gptkbp:website |
http://genetics.bwh.harvard.edu/pph2/
|
| gptkbp:bfsParent |
gptkb:CADD_scores
|
| gptkbp:bfsLayer |
7
|