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gptkbp:instanceOf
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gptkb:software
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gptkbp:citation
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Adzhubei IA, et al. Nat Methods. 2010
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gptkbp:developedBy
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gptkb:Brigham_and_Women's_Hospital
gptkb:Harvard_Medical_School
Sunyaev Lab
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gptkbp:field
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genetics
bioinformatics
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gptkbp:firstReleased
|
2010
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gptkbp:format
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gptkb:FASTA
tab-delimited
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gptkbp:fullName
|
Polymorphism Phenotyping v2
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gptkbp:hasVersion
|
2.2.2
2.2.3
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gptkbp:input
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gptkb:protein
gptkb:amino_acid_substitution
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gptkbp:license
|
free for academic use
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gptkbp:output
|
benign/possibly damaging/probably damaging classification
prediction of mutation effect
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gptkbp:predicts
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functional effect of non-synonymous SNPs
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gptkbp:relatedTo
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gptkb:SIFT
gptkb:MutationTaster
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gptkbp:speciesSupported
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gptkb:human
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gptkbp:supportsAlgorithm
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gptkb:machine_learning
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gptkbp:usedFor
|
predicting impact of amino acid substitutions
assessing possible impact of missense mutations
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gptkbp:uses
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phylogenetic features
sequence-based features
structure-based features
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gptkbp:website
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http://genetics.bwh.harvard.edu/pph2/
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gptkbp:bfsParent
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gptkb:PolyPhen-2_scores
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gptkbp:bfsLayer
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7
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https://www.w3.org/2000/01/rdf-schema#label
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PolyPhen-2
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