Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:software
|
| gptkbp:citation |
Adzhubei IA, et al. Nat Methods. 2010
|
| gptkbp:developedBy |
gptkb:Brigham_and_Women's_Hospital
gptkb:Harvard_Medical_School Sunyaev Lab |
| gptkbp:field |
genetics
bioinformatics |
| gptkbp:firstReleased |
2010
|
| gptkbp:format |
gptkb:FASTA
tab-delimited |
| gptkbp:fullName |
Polymorphism Phenotyping v2
|
| gptkbp:hasVersion |
2.2.2
2.2.3 |
| https://www.w3.org/2000/01/rdf-schema#label |
PolyPhen-2
|
| gptkbp:input |
gptkb:protein
amino acid substitution |
| gptkbp:license |
free for academic use
|
| gptkbp:output |
benign/possibly damaging/probably damaging classification
prediction of mutation effect |
| gptkbp:predicts |
functional effect of non-synonymous SNPs
|
| gptkbp:relatedTo |
gptkb:SIFT
gptkb:MutationTaster |
| gptkbp:speciesSupported |
gptkb:human
|
| gptkbp:supportsAlgorithm |
gptkb:machine_learning
|
| gptkbp:usedFor |
predicting impact of amino acid substitutions
assessing possible impact of missense mutations |
| gptkbp:uses |
phylogenetic features
sequence-based features structure-based features |
| gptkbp:website |
http://genetics.bwh.harvard.edu/pph2/
|
| gptkbp:bfsParent |
gptkb:PolyPhen-2_scores
|
| gptkbp:bfsLayer |
7
|