Poliovirus

GPTKB entity

Statements (58)
Predicate Object
gptkbp:instanceOf gptkb:virus
gptkbp:Baltimore_classification Group IV (+)ssRNA viruses
gptkbp:biosafetyLevel BSL-2 (attenuated), BSL-3 (wild type)
gptkbp:caps gptkb:VP1
gptkb:VP2
gptkb:VP3
gptkb:VP4
gptkbp:cause gptkb:Poliomyelitis
gptkbp:containsSerotype Type 1
Type 2
Type 3
gptkbp:decommissioned gptkb:Heat
gptkb:Formalin
Chlorine
gptkbp:discoveredBy gptkb:Karl_Landsteiner
gptkb:Erwin_Popper
gptkbp:discoveredIn 1908
gptkbp:enveloped No
gptkbp:eradicationEffort Global Polio Eradication Initiative
gptkbp:family gptkb:Picornaviridae
gptkbp:firstOralVaccineDevelopedBy gptkb:Albert_Sabin
gptkbp:firstVaccineDevelopedBy gptkb:Jonas_Salk
gptkbp:genomeSense Positive-sense
gptkbp:genomeType Single-stranded RNA
gptkbp:genus gptkb:virus
gptkbp:hostedBy gptkb:Humans
https://www.w3.org/2000/01/rdf-schema#label Poliovirus
gptkbp:incubationPeriod 7-14 days
gptkbp:infectiousPeriod 7-10 days before and after onset of symptoms
gptkbp:notableContributor First virus to be synthesized in vitro
Used in molecular biology research
gptkbp:notableFeature No animal reservoir
High mutation rate
gptkbp:notableLaboratoryStrain gptkb:Mahoney_strain
gptkbp:notableOutbreaks gptkb:20th_century_polio_epidemics
gptkbp:notableResearchYear 2002
gptkbp:order gptkb:Picornavirales
gptkbp:recipient gptkb:CD155_(PVR)
gptkbp:replicationSite gptkb:Cytoplasm
gptkbp:species gptkb:Enterovirus_C
gptkbp:structure Icosahedral
gptkbp:symptom Fever
Fatigue
Headache
Vomiting
Paralysis
Neck stiffness
Pain in limbs
gptkbp:transmissionRoute Fecal-oral
Oral-oral
gptkbp:vaccineAvailable Yes
gptkbp:vaccineType gptkb:Inactivated_poliovirus_vaccine
gptkb:Oral_poliovirus_vaccine
gptkbp:WHOStatus Type 1 still endemic in some countries
Type 2 eradicated (2015)
Type 3 eradicated (2019)
gptkbp:bfsParent gptkb:virus
gptkbp:bfsLayer 5