Phospholipase D

GPTKB entity

Statements (36)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:associatedWith neurodegenerative diseases
cancer progression
gptkbp:CASNumber 9000-85-5
gptkbp:catalyzes hydrolysis of phosphatidylcholine
gptkbp:cofactor calcium
phosphatidylinositol 4,5-bisphosphate
gptkbp:discoveredBy snake venom
gptkbp:EC_number 3.1.4.4
gptkbp:encodedBy PLD1 gene
PLD2 gene
gptkbp:foundIn gptkb:Bacteria
animals
fungi
plants
gptkbp:GO_term GO:0004630
gptkbp:hasIsoform PLD1
PLD2
https://www.w3.org/2000/01/rdf-schema#label Phospholipase D
gptkbp:inhibitedBy propranolol
primary alcohols
gptkbp:involves cell proliferation
signal transduction
phagocytosis
membrane trafficking
vesicle transport
gptkbp:product gptkb:choline
phosphatidic acid
gptkbp:structure contains HKD motif
gptkbp:UniProtID O14939 (PLD2, human)
P23786 (PLD1, human)
gptkbp:used_in gptkb:biotechnology
food industry
lipid modification
gptkbp:bfsParent gptkb:Phospholipase
gptkbp:bfsLayer 7