Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
antineoplastic agent |
| gptkbp:administeredBy |
oral tablet
intravenous injection |
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
L01AA03
|
| gptkbp:brand |
gptkb:Alkeran
|
| gptkbp:CASNumber |
148-82-3
|
| gptkbp:category |
cytotoxic drug
nitrogen mustard derivative |
| gptkbp:discoveredBy |
Alexander Haddow
|
| gptkbp:eliminationHalfLife |
renal
|
| gptkbp:hasMolecularFormula |
C13H18Cl2N2O2
|
| https://www.w3.org/2000/01/rdf-schema#label |
Phenylalanine mustard
|
| gptkbp:mechanismOfAction |
DNA crosslinking
|
| gptkbp:meltingPoint |
183-189°C
|
| gptkbp:otherName |
Melphalan
|
| gptkbp:sideEffect |
nausea
vomiting hair loss bone marrow suppression |
| gptkbp:solubility |
slightly soluble in water
|
| gptkbp:usedFor |
gptkb:cancer
melanoma multiple myeloma |
| gptkbp:bfsParent |
gptkb:melphalan
|
| gptkbp:bfsLayer |
7
|