Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:associatedWith |
cerebral malaria
pregnancy-associated malaria |
gptkbp:binds |
gptkb:ICAM-1
gptkb:CSA gptkb:CD36 endothelial receptors |
gptkbp:cause |
sequestration of infected erythrocytes
|
gptkbp:discoveredIn |
1990s
|
gptkbp:domain |
CIDR domain
DBL domain |
gptkbp:encodedBy |
var gene family
|
gptkbp:foundIn |
gptkb:Plasmodium_falciparum
|
gptkbp:function |
immune evasion
antigenic variation cytoadherence |
https://www.w3.org/2000/01/rdf-schema#label |
PfEMP1
|
gptkbp:location |
surface of infected erythrocytes
|
gptkbp:numberOfGenes |
~60 per parasite genome
|
gptkbp:role |
malaria pathogenesis
|
gptkbp:variationMechanism |
gene switching
|
gptkbp:bfsParent |
gptkb:Plasmodium_falciparum
|
gptkbp:bfsLayer |
5
|