PfEMP1

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:associatedWith cerebral malaria
pregnancy-associated malaria
gptkbp:binds gptkb:ICAM-1
gptkb:CSA
gptkb:CD36
endothelial receptors
gptkbp:cause sequestration of infected erythrocytes
gptkbp:discoveredIn 1990s
gptkbp:domain CIDR domain
DBL domain
gptkbp:encodedBy var gene family
gptkbp:foundIn gptkb:Plasmodium_falciparum
gptkbp:function immune evasion
antigenic variation
cytoadherence
https://www.w3.org/2000/01/rdf-schema#label PfEMP1
gptkbp:location surface of infected erythrocytes
gptkbp:numberOfGenes ~60 per parasite genome
gptkbp:role malaria pathogenesis
gptkbp:variationMechanism gene switching
gptkbp:bfsParent gptkb:Plasmodium_falciparum
gptkbp:bfsLayer 5