|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:administeredBy
|
oral
intramuscular
intravenous
|
|
gptkbp:ATCCode
|
gptkb:J01C
|
|
gptkbp:CASNumber
|
61-33-6 (Penicillin G)
|
|
gptkbp:category
|
natural product
antimicrobial
|
|
gptkbp:cause
|
gptkb:Clostridioides_difficile_infection
nausea
diarrhea
seizures (rare)
|
|
gptkbp:chemicalFormula
|
C16H18N2O4S (Penicillin G)
|
|
gptkbp:contraindication
|
penicillin allergy
|
|
gptkbp:discoveredBy
|
gptkb:Alexander_Fleming
|
|
gptkbp:discoveredIn
|
1928
|
|
gptkbp:eliminatedIn
|
renal
|
|
gptkbp:firstClinicalUse
|
1941
|
|
gptkbp:firstMarketedBy
|
gptkb:Pfizer
|
|
gptkbp:firstProduced
|
1940s
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Penicillin
|
|
gptkbp:includedIn
|
gptkb:United_States_Pharmacopeia
gptkb:WHO_Model_List_of_Essential_Medicines
gptkb:British_National_Formulary
|
|
gptkbp:introducedIn
|
gptkb:World_War_II
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits cell wall synthesis
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:notEffectiveAgainst
|
fungal infections
viral infections
parasitic infections
|
|
gptkbp:origin
|
mold
|
|
gptkbp:pregnancyCategory
|
generally safe
|
|
gptkbp:producedBy
|
gptkb:Penicillium_fungi
|
|
gptkbp:relatedTo
|
gptkb:amoxicillin
gptkb:methicillin
gptkb:ampicillin
|
|
gptkbp:resistanceObservedIn
|
some bacteria
|
|
gptkbp:sideEffect
|
allergic reaction
anaphylaxis
rash
|
|
gptkbp:spectrumOfActivity
|
mainly Gram-positive bacteria
|
|
gptkbp:storage
|
cool, dry place
|
|
gptkbp:type
|
gptkb:antibiotic
|
|
gptkbp:usedFor
|
bacterial infections
|
|
gptkbp:bfsParent
|
gptkb:Antibiotics
|
|
gptkbp:bfsLayer
|
4
|