Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
bone disorder |
| gptkbp:affects |
bone remodeling
|
| gptkbp:alsoKnownAs |
gptkb:osteitis_deformans
|
| gptkbp:associatedWith |
increased alkaline phosphatase
mosaic pattern of lamellar bone viral infection hypothesis |
| gptkbp:cause |
arthritis
fractures bone pain bone deformities |
| gptkbp:characterizedBy |
abnormal bone destruction and regrowth
|
| gptkbp:commonIn |
skull
femur pelvis spine tibia |
| gptkbp:complication |
heart failure
hearing loss osteosarcoma |
| gptkbp:diagnosedBy |
gptkb:X-rays
blood test (alkaline phosphatase) bone scan |
| gptkbp:differentialDiagnosis |
gptkb:fibrous_dysplasia
gptkb:bone bone metastases |
| gptkbp:etiology |
unknown
|
| gptkbp:firstDescribed |
gptkb:Sir_James_Paget
1877 |
| https://www.w3.org/2000/01/rdf-schema#label |
Paget's disease of bone
|
| gptkbp:ICD-10_code |
gptkb:M88
|
| gptkbp:MeSH_ID |
D010146
|
| gptkbp:OMIM |
167250
|
| gptkbp:prevalence |
more common in older adults
more common in people of European descent |
| gptkbp:riskFactor |
age
family history genetic factors |
| gptkbp:symptom |
joint pain
bone pain bowed limbs deafness (if skull involved) enlarged bones warmth over affected bone |
| gptkbp:treatment |
gptkb:bisphosphonates
gptkb:calcitonin surgery pain relievers |
| gptkbp:bfsParent |
gptkb:James_Paget
gptkb:rhabdomyosarcoma gptkb:Fosamax gptkb:Zometa |
| gptkbp:bfsLayer |
5
|