Statements (69)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:DNA
|
| gptkbp:associated_with |
pluripotency
|
| gptkbp:code |
chromosome 6
|
| gptkbp:function |
gptkb:DNA
|
| gptkbp:genetic_studies |
gptkb:disease
|
| gptkbp:has_role |
cell differentiation
|
| gptkbp:has_variants |
SNPs
|
| https://www.w3.org/2000/01/rdf-schema#label |
POU5 F1
|
| gptkbp:interacts_with |
gptkb:NANOG
gptkb:SOX2 |
| gptkbp:involved_in |
gptkb:developers
|
| gptkbp:is_associated_with |
gptkb:neurodegenerative_diseases
stem cell maintenance cellular reprogramming cancer stem cells metabolic regulation stem cell tumors |
| gptkbp:is_essential_for |
early embryogenesis
|
| gptkbp:is_expressed_in |
embryonic tissues
adult stem cells somatic cells germ cells embryonic stem cells early development neural stem cells pluripotent stem cells cardiac stem cells placental tissues early embryos |
| gptkbp:is_involved_in |
gptkb:embryonic_development
cell cycle regulation cellular homeostasis gene regulation immune response transcriptional activation cell signaling pathways cellular aging tissue regeneration neurogenesis organogenesis gene expression regulation vascular development epigenetic regulation cell fate determination reproductive biology cellular repair mechanisms reprogramming of somatic cells cellular identity stem cell differentiation cellular signaling. |
| gptkbp:is_linked_to |
cellular stress response
genetic stability infertility developmental disorders stem cell plasticity |
| gptkbp:is_part_of |
transcriptional regulatory network
gene regulatory networks pluripotency network |
| gptkbp:is_regulated_by |
transcription factors
micro RNAs |
| gptkbp:is_studied_in |
cancer research
|
| gptkbp:knockouts |
enhancers
|
| gptkbp:located_in |
gptkb:Atom
|
| gptkbp:orthologs |
other species
|
| gptkbp:part_of |
stem cell network
|
| gptkbp:regulates |
self-renewal
|
| gptkbp:targets |
gptkb:pharmaceuticals
|
| gptkbp:bfsParent |
gptkb:Oct4
|
| gptkbp:bfsLayer |
5
|