Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
nuclear body
|
| gptkbp:alsoKnownAs |
PML nuclear bodies
PML oncogenic domains |
| gptkbp:associatedWith |
gptkb:acute_promyelocytic_leukemia
|
| gptkbp:category |
subnuclear structure
|
| gptkbp:composedOf |
gptkb:PML_protein
SP100 protein SUMO proteins DAXX protein |
| gptkbp:discoveredBy |
K. de Thé
|
| gptkbp:dynamic |
yes
|
| gptkbp:firstDescribed |
1991
|
| gptkbp:function |
apoptosis
DNA damage response regulation of gene expression tumor suppression antiviral response |
| https://www.w3.org/2000/01/rdf-schema#label |
PML bodies
|
| gptkbp:interactsWith |
gptkb:CBP_protein
gptkb:p53_protein SUMOylated proteins |
| gptkbp:interruptedBy |
PML-RARα fusion protein
|
| gptkbp:locatedIn |
cell nucleus
|
| gptkbp:namedAfter |
gptkb:PML_protein
|
| gptkbp:numberPerCell |
5-30
|
| gptkbp:relatedTo |
gptkb:Cajal_bodies
nucleolus nuclear speckles |
| gptkbp:size |
0.2-1.0 μm
|
| gptkbp:visualizes |
immunofluorescence microscopy
|
| gptkbp:bfsParent |
gptkb:Nucleus_(in_mammals)
gptkb:Nuclei |
| gptkbp:bfsLayer |
7
|