Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
PI3K inhibitor |
| gptkbp:CASNumber |
154447-36-6
|
| gptkbp:discoveredBy |
gptkb:Lilly_Research_Laboratories
|
| gptkbp:has_solubility_in_DMSO |
50 mM
|
| gptkbp:hasMolecularFormula |
C19H17NO3
|
| gptkbp:hasSMILES |
C1COCCN1C2=CC3=C(C=C2)C(=O)C(=C(O3)C4=CC=CC=C4)
|
| https://www.w3.org/2000/01/rdf-schema#label |
PI3K inhibitor LY294002
|
| gptkbp:inhibitedBy |
gptkb:casein_kinase_2
phosphoinositide 3-kinases |
| gptkbp:is_cell-permeable |
true
|
| gptkbp:is_not_approved_for_clinical_use |
true
|
| gptkbp:IUPACName |
gptkb:2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
|
| gptkbp:mechanismOfAction |
ATP-competitive inhibitor
|
| gptkbp:meltingPoint |
215-217 °C
|
| gptkbp:molecularWeight |
307.34 g/mol
|
| gptkbp:PubChem_CID |
gptkb:CHEMBL958
3973 3836 |
| gptkbp:synonym |
gptkb:LY-294002
gptkb:LY_294002 gptkb:LY294002 |
| gptkbp:target |
gptkb:PIK3CA
gptkb:PIK3CB gptkb:PIK3CD gptkb:PIK3CG |
| gptkbp:used_in |
biological research
|
| gptkbp:bfsParent |
gptkb:LY294002
|
| gptkbp:bfsLayer |
5
|