Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:author |
Ang, H.C.
Fersht, A.R. Joerger, A.C. |
| gptkbp:chain |
1
A |
| gptkbp:citation |
gptkb:J._Mol._Biol.
2006 Structural basis of p53 core domain stability: effects of hydrogen bond networks, salt bridges, and metal ligands |
| gptkbp:citationPages |
917-927
|
| gptkbp:citationVolume |
356
|
| gptkbp:depositedDate |
2004-08-10
|
| gptkbp:experimentalMethod |
X-ray crystallography
|
| https://www.w3.org/2000/01/rdf-schema#label |
PDB:1WDC
|
| gptkbp:length |
191 amino acids
|
| gptkbp:ligand |
gptkb:water
Zinc ion |
| gptkbp:macromoleculeType |
gptkb:protein
|
| gptkbp:mutationAssociatedWith |
Missense
R249S |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
1WDC
|
| gptkbp:protein_name |
Tumor protein p53
|
| gptkbp:releaseDate |
2004-09-14
|
| gptkbp:resolution |
2.10 Å
|
| gptkbp:structureDeterminationMethod |
X-ray diffraction
|
| gptkbp:title |
Crystal structure of the human p53 core domain mutant R249S
|
| gptkbp:UniProtID |
P04637
|
| gptkbp:bfsParent |
gptkb:P05981
|
| gptkbp:bfsLayer |
8
|