|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
gptkb:OTTHUMP00000021264
gptkb:PRL1
gptkb:PRL
pre-B-cell leukemia transcription factor 1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:biologicalProcess
|
embryonic development
organogenesis
regulation of transcription
protein binding
DNA binding
|
|
gptkbp:discoveredBy
|
1990
|
|
gptkbp:domain
|
homeobox domain
PBC-A domain
PBC-B domain
|
|
gptkbp:encodedBy
|
gptkb:PBX1_gene
|
|
gptkbp:Entrez_Gene_ID
|
5087
ENSG00000185630
|
|
gptkbp:family
|
gptkb:TALE_homeobox_family
|
|
gptkbp:function
|
transcription factor
|
|
gptkbp:HGNC_ID
|
HGNC:8635
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PBX1 (human)
|
|
gptkbp:interactsWith
|
gptkb:HOXA9
gptkb:MEIS1
gptkb:PREP1
|
|
gptkbp:length
|
430 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_1q23
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
PBX1 (mouse)
PBX1 (rat)
|
|
gptkbp:postTranslationalModification
|
phosphorylation
acetylation
|
|
gptkbp:RefSeq
|
NP_002576.1
|
|
gptkbp:significance
|
fusion with E2A gene in t(1;19) translocation
associated with pre-B-cell acute lymphoblastic leukemia
|
|
gptkbp:UniProtID
|
P40424
|
|
gptkbp:bfsParent
|
gptkb:Pbx1
|
|
gptkbp:bfsLayer
|
7
|