|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
Adenosine deaminase acting on RNA 1
Double-stranded RNA-specific adenosine deaminase
|
|
gptkbp:associatedWith
|
Aicardi-Goutieres syndrome
Dyschromatosis symmetrica hereditaria
|
|
gptkbp:biologicalProcess
|
RNA binding
hydrolase activity
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
|
|
gptkbp:domain
|
deaminase domain
dsRNA binding domain
|
|
gptkbp:encodedBy
|
ADAR gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSP00000367402
|
|
gptkbp:enzymeCommissionNumber
|
3.5.4.37
|
|
gptkbp:function
|
RNA editing
A-to-I editing
|
|
gptkbp:GO
|
GO:0003723
GO:0003968
|
|
gptkbp:HGNC_ID
|
HGNC:261
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P78563 (ADAR)
|
|
gptkbp:InterPro
|
IPR002466
IPR007025
|
|
gptkbp:KEGGID
|
hsa:103
|
|
gptkbp:length
|
1226 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 1
|
|
gptkbp:mass
|
139 kDa
|
|
gptkbp:OMIM
|
103690
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Adar1
zebrafish adar
|
|
gptkbp:PDB
|
5ED1
5HP2
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
|
|
gptkbp:proteinFamily
|
PF02267
PF02137
|
|
gptkbp:Reactome
|
R-HSA-8953854
|
|
gptkbp:RefSeq
|
NP_001102
|
|
gptkbp:subunit
|
homodimer
|
|
gptkbp:tissue_specificity
|
gptkb:cancer
brain
liver
|
|
gptkbp:UniProtID
|
P78563
|
|
gptkbp:bfsParent
|
gptkb:Adenosine_deaminase_acting_on_RNA
|
|
gptkbp:bfsLayer
|
7
|