|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Arg
Tyrosine-protein kinase ABL2
|
|
gptkbp:associatedWith
|
gptkb:cancer
|
|
gptkbp:biologicalProcess
|
signal transduction
ATP binding
protein tyrosine kinase activity
actin cytoskeleton organization
|
|
gptkbp:cellularComponent
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:Entrez_Gene_ID
|
27
ENSP00000367468
|
|
gptkbp:enzymeCommissionNumber
|
2.7.10.2
|
|
gptkbp:gene
|
ABL2
|
|
gptkbp:has_3D_structure_in_PDB
|
yes
|
|
gptkbp:has_actin-binding_domain
|
yes
|
|
gptkbp:has_kinase_domain
|
yes
|
|
gptkbp:has_phosphoprotein
|
yes
|
|
gptkbp:has_SH2_domain
|
yes
|
|
gptkbp:has_SH3_domain
|
yes
|
|
gptkbp:HGNC_ID
|
76
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P52333
|
|
gptkbp:involves
|
apoptosis
cell differentiation
cell proliferation
cell migration
cell adhesion
|
|
gptkbp:is_a_member_of_protein_family
|
ABL family
tyrosine-protein kinase family
|
|
gptkbp:is_a_target_for
|
tyrosine kinase inhibitors
|
|
gptkbp:is_expressed_in
|
various tissues
|
|
gptkbp:is_reviewed_in_UniProt
|
true
|
|
gptkbp:length
|
1121
|
|
gptkbp:locatedOnChromosome
|
1
|
|
gptkbp:location
|
1q25
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
4J3J
5MO4
5MO5
5MO6
5MO7
5MO8
5MO9
5MOA
5MOB
5MOC
5MOD
5MOE
5MOF
5MOG
5MOH
5MOI
5MOJ
5MOK
5MOL
5MOM
5MON
5MOO
5MOP
5MOQ
5MOR
5MOS
5MOT
5MOU
5MOV
5MOW
5MOX
5MOY
5MOZ
|
|
gptkbp:protein_name
|
Abelson tyrosine-protein kinase 2
|
|
gptkbp:RefSeq
|
NP_005151.2
|
|
gptkbp:UniProtID
|
gptkb:P52333
|
|
gptkbp:bfsParent
|
gptkb:JAN3
gptkb:JAK3
|
|
gptkbp:bfsLayer
|
7
|