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gptkbp:instanceOf
|
UniProt accession number
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|
gptkbp:alternativeName
|
gptkb:CYP2C9v
P450C2C
CYPIIC9
Cytochrome P450, family 2, subfamily C, polypeptide 9
|
|
gptkbp:associatedWith
|
NSAID metabolism
Phenytoin toxicity
Warfarin sensitivity
|
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gptkbp:cofactor
|
Heme
|
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gptkbp:database
|
gptkb:UniProt
|
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gptkbp:EC_number
|
1.14.14.1
|
|
gptkbp:Entrez_Gene_ID
|
1559
ENSG00000138109
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gptkbp:function
|
Monooxygenase involved in drug metabolism
|
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gptkbp:gene
|
gptkb:CYP2C9
|
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gptkbp:GO
|
GO:0004497
GO:0005506
GO:0005783
GO:0020037
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gptkbp:hasBiologicalActivity
|
Drug metabolism
Oxidation of xenobiotics
|
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gptkbp:hasPolymorphism
|
Yes
|
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gptkbp:HGNC_ID
|
2593
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P22813
|
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gptkbp:InterPro
|
IPR001128
|
|
gptkbp:KEGGID
|
hsa:1559
|
|
gptkbp:lastAnnotationUpdate
|
2022-02-23
|
|
gptkbp:latestReleaseVersion
|
1997-11-01
|
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gptkbp:length
|
490 amino acids
|
|
gptkbp:locatedOnChromosome
|
10q23.33
Chromosome 10
|
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gptkbp:molecularWeight
|
55,766 Da
|
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gptkbp:name
|
CP2C9_HUMAN
|
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gptkbp:organism
|
gptkb:Homo_sapiens
9606
|
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gptkbp:pathway
|
Drug metabolism - cytochrome P450
Metabolism of xenobiotics by cytochrome P450
|
|
gptkbp:PDB
|
1OG5
1R90
1R9O
|
|
gptkbp:protein_name
|
Cytochrome P450 2C9
|
|
gptkbp:proteinFamily
|
PF00067
|
|
gptkbp:Reactome
|
R-HSA-211958
|
|
gptkbp:refersTo
|
Human protein: Cytochrome P450 2C9
|
|
gptkbp:RefSeq
|
NP_000762.2
|
|
gptkbp:sequenceStatus
|
Reviewed
|
|
gptkbp:sequenceVersion
|
2
|
|
gptkbp:subcellularLocation
|
gptkb:Endoplasmic_reticulum
Microsome
|
|
gptkbp:UniProtID
|
gptkb:P22813
|
|
gptkbp:bfsParent
|
gptkb:Drosophila_single-minded_(sim)_gene
|
|
gptkbp:bfsLayer
|
7
|