Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
organelle
|
| gptkbp:abbreviation |
gptkb:ER
|
| gptkbp:associatedWith |
gptkb:Golgi_apparatus
lysosomes peroxisomes |
| gptkbp:compatibleWith |
prokaryotic cells
|
| gptkbp:component |
endomembrane system
|
| gptkbp:connectedTo |
nuclear envelope
|
| gptkbp:discoveredBy |
gptkb:Emilio_Veratti
|
| gptkbp:discoveredIn |
1902
|
| gptkbp:dysregulationAssociatedWith |
gptkb:cancer
gptkb:diabetes neurodegenerative diseases |
| gptkbp:foundIn |
eukaryotic cells
|
| gptkbp:function |
lipid synthesis
protein synthesis detoxification calcium storage |
| gptkbp:hasType |
gptkb:smooth_endoplasmic_reticulum
rough endoplasmic reticulum |
| https://www.w3.org/2000/01/rdf-schema#label |
Endoplasmic reticulum
|
| gptkbp:involvedIn |
histone modification
vesicle formation glycogen breakdown calcium ion signaling detoxification of drugs lipoprotein production membrane biogenesis synthesis of steroid hormones transport of proteins |
| gptkbp:location |
gptkb:cytoplasm
|
| gptkbp:malfunctionLeadsTo |
unfolded protein response
ER stress |
| gptkbp:membraneType |
phospholipid bilayer
|
| gptkbp:presentIn |
animal cells
plant cells |
| gptkbp:role |
signal transduction
cellular homeostasis cellular stress response |
| gptkbp:rough_ER_abundantIn |
secretory cells
|
| gptkbp:rough_ER_contains |
ribosomes
|
| gptkbp:rough_ER_function |
protein folding
|
| gptkbp:smooth_ER_abundantIn |
muscle cells
liver cells |
| gptkbp:smooth_ER_function |
lipid metabolism
carbohydrate metabolism |
| gptkbp:smooth_ER_lacks |
ribosomes
|
| gptkbp:structure |
network of membranes
|
| gptkbp:bfsParent |
gptkb:Cell
|
| gptkbp:bfsLayer |
5
|