Mesenchymal Stem Cell Therapy
GPTKB entity
Statements (46)
Predicate | Object |
---|---|
gptkbp:instanceOf |
Medical Treatment
|
gptkbp:administeredBy |
gptkb:Injection
Intravenous Infusion Local Application |
gptkbp:alternativeTo |
Hematopoietic Stem Cell Therapy
|
gptkbp:approvedBy |
Graft-versus-host Disease (in some countries)
|
gptkbp:clinicalTrialPhase |
Ongoing
|
gptkbp:compatibleWith |
Most Indications (in the United States)
|
gptkbp:controversy |
Regulatory Issues
Unproven Claims Variable Efficacy |
https://www.w3.org/2000/01/rdf-schema#label |
Mesenchymal Stem Cell Therapy
|
gptkbp:introducedIn |
1990s
|
gptkbp:mechanismOfAction |
Anti-inflammatory Effects
Differentiation into Target Cells Immunomodulation Paracrine Signaling |
gptkbp:regulates |
FDA (in the United States)
|
gptkbp:relatedTo |
gptkb:Regenerative_Medicine
gptkb:Stem_Cell_Therapy Cell-based Therapy |
gptkbp:riskFactor |
Infection
Thrombosis Tumor Formation Immune Reaction |
gptkbp:source |
Umbilical Cord
Adipose Tissue Bone Marrow Dental Pulp |
gptkbp:status |
Investigational for Many Indications
|
gptkbp:studiedBy |
Hospitals
Academic Institutions Biotechnology Companies |
gptkbp:usedFor |
gptkb:Osteoarthritis
gptkb:Graft-versus-host_Disease gptkb:Regenerative_Medicine Neurological Disorders Cardiovascular Diseases Autoimmune Diseases Tissue Repair Wound Healing Cartilage Repair Orthopedic Conditions |
gptkbp:uses |
Mesenchymal Stem Cells
|
gptkbp:bfsParent |
gptkb:Cell_Therapy
|
gptkbp:bfsLayer |
6
|