Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
beta-lactamase
|
| gptkbp:detects |
PCR
Carba NP test immunochromatographic assay |
| gptkbp:encodedBy |
blaOXA-48 gene
|
| gptkbp:firstDescribed |
gptkb:Turkey
2001 |
| gptkbp:foundIn |
gptkb:Enterobacteriaceae
gptkb:Bacteria gptkb:Klebsiella_pneumoniae |
| gptkbp:hasVariant |
OXA-163
OXA-181 OXA-232 OXA-244 |
| https://www.w3.org/2000/01/rdf-schema#label |
OXA-48-like beta-lactamase
|
| gptkbp:inhibitedBy |
gptkb:clavulanic_acid
gptkb:sulbactam tazobactam avibactam |
| gptkbp:mechanismOfAction |
hydrolyzes beta-lactam ring
|
| gptkbp:molecularWeight |
~28 kDa
|
| gptkbp:publicHealthConcern |
yes
|
| gptkbp:resistantTo |
penicillins
carbapenem antibiotics cephalosporins (weakly) |
| gptkbp:spreadTo |
hospital outbreaks
|
| gptkbp:subclassOf |
class D beta-lactamase
|
| gptkbp:transmittedBy |
plasmids
|
| gptkbp:bfsParent |
gptkb:antimicrobial_resistance_gene_OXA-48-like
|
| gptkbp:bfsLayer |
8
|