OX40 ligand (OX40L)

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName CD252
Tumor necrosis factor ligand superfamily member 4
gptkbp:binds OX40 (CD134)
gptkbp:encodedBy TNFSF4 gene
gptkbp:expressedIn gptkb:B_cells
dendritic cells
macrophages
antigen-presenting cells
gptkbp:function promotes T cell proliferation
co-stimulatory molecule in T cell activation
enhances T cell survival
https://www.w3.org/2000/01/rdf-schema#label OX40 ligand (OX40L)
gptkbp:involvedIn autoimmune diseases
immune response
allergic inflammation
gptkbp:locatedOnChromosome chromosome 1q25
gptkbp:memberOf tumor necrosis factor (TNF) superfamily
gptkbp:potentialTherapeuticTarget immunotherapy
autoimmune disease therapy
gptkbp:species gptkb:Homo_sapiens
gptkbp:UniProtID P23510
gptkbp:bfsParent gptkb:CD134
gptkb:OX40
gptkbp:bfsLayer 8