Statements (21)
Predicate | Object |
---|---|
gptkbp:instanceOf |
oncolytic virus
|
gptkbp:basedOn |
herpes simplex virus type 1 (HSV-1)
|
gptkbp:clinicalTrialPhase |
Phase 1
NCT04348916 |
gptkbp:deliveredBy |
intratumoral
|
gptkbp:designedFor |
intratumoral injection
|
gptkbp:developedBy |
Oncorus, Inc.
|
gptkbp:expressedIn |
gptkb:GM-CSF
gptkb:IL-15 gptkb:IL-12 CCL4 anti-CTLA-4 antibody anti-PD-1 antibody |
gptkbp:geneticallyModified |
yes
|
https://www.w3.org/2000/01/rdf-schema#label |
ONCR-177
|
gptkbp:mechanismOfAction |
selectively replicates in tumor cells
stimulates anti-tumor immune response |
gptkbp:status |
investigational
|
gptkbp:target |
solid tumors
|
gptkbp:bfsParent |
gptkb:Oncorus
|
gptkbp:bfsLayer |
8
|