ONCR-177

GPTKB entity

Statements (21)
Predicate Object
gptkbp:instanceOf oncolytic virus
gptkbp:basedOn herpes simplex virus type 1 (HSV-1)
gptkbp:clinicalTrialPhase Phase 1
NCT04348916
gptkbp:deliveredBy intratumoral
gptkbp:designedFor intratumoral injection
gptkbp:developedBy Oncorus, Inc.
gptkbp:expressedIn gptkb:GM-CSF
gptkb:IL-15
gptkb:IL-12
CCL4
anti-CTLA-4 antibody
anti-PD-1 antibody
gptkbp:geneticallyModified yes
https://www.w3.org/2000/01/rdf-schema#label ONCR-177
gptkbp:mechanismOfAction selectively replicates in tumor cells
stimulates anti-tumor immune response
gptkbp:status investigational
gptkbp:target solid tumors
gptkbp:bfsParent gptkb:Oncorus
gptkbp:bfsLayer 8