Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:SLC22A6
hOAT1 solute carrier family 22 member 6 |
| gptkbp:encodedBy |
gptkb:SLC22A6
|
| gptkbp:Entrez_Gene_ID |
9356
|
| gptkbp:expressedIn |
proximal tubule
|
| gptkbp:fullName |
Organic Anion Transporter 1
|
| gptkbp:function |
transports organic anions
mediates renal secretion of drugs |
| gptkbp:gene |
gptkb:SLC22A6
|
| gptkbp:HGNC_ID |
10965
|
| https://www.w3.org/2000/01/rdf-schema#label |
OAT1
|
| gptkbp:inhibitedBy |
gptkb:probenecid
nonsteroidal anti-inflammatory drugs |
| gptkbp:locatedOnChromosome |
11q12.3
|
| gptkbp:location |
gptkb:kidney
|
| gptkbp:OMIM |
602631
|
| gptkbp:significance |
nephrotoxicity
drug-drug interactions |
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:substrate |
antibiotics
antiviral drugs diuretics para-aminohippurate urate |
| gptkbp:transmembraneDomains |
true
|
| gptkbp:transporterFamily |
gptkb:SLC22
|
| gptkbp:UniProtID |
Q4U2R8
|
| gptkbp:bfsParent |
gptkb:solute_carrier_family_22
gptkb:SLC22A6 |
| gptkbp:bfsLayer |
7
|