Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
double-stranded RNA
|
| gptkbp:associatedWith |
autoimmune diseases
COVID-19 severity viral infection resistance |
| gptkbp:discoveredBy |
1980s
|
| gptkbp:encodes |
OAS proteins
|
| gptkbp:fullName |
2'-5'-oligoadenylate synthetase genes
|
| gptkbp:function |
innate immunity
antiviral response |
| https://www.w3.org/2000/01/rdf-schema#label |
OAS genes
|
| gptkbp:location |
chromosome 12q24.2
|
| gptkbp:mechanismOfAction |
activates RNase L
synthesizes 2'-5'-linked oligoadenylates |
| gptkbp:member |
gptkb:OAS2
gptkb:OAS3 gptkb:OASL gptkb:OAS1 |
| gptkbp:orthologIn |
present in mammals
|
| gptkbp:pathway |
interferon signaling pathway
|
| gptkbp:regulates |
induced by interferons
|
| gptkbp:bfsParent |
gptkb:2'-5'-oligoadenylate_synthetase_family
|
| gptkbp:bfsLayer |
7
|