Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
viral infection susceptibility
|
| gptkbp:biologicalProcess |
nucleotidyltransferase activity
defense response to virus interferon-gamma-mediated signaling pathway |
| gptkbp:discoveredBy |
1980s
|
| gptkbp:encodes |
2'-5'-oligoadenylate synthetase 2
|
| gptkbp:Entrez_Gene_ID |
ENSG00000111335
4939 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:fullName |
2'-5'-oligoadenylate synthetase 2
|
| gptkbp:function |
involved in innate immune response
activates RNase L synthesizes 2',5'-oligoadenylates from ATP |
| https://www.w3.org/2000/01/rdf-schema#label |
OAS2
|
| gptkbp:length |
719 amino acids
|
| gptkbp:locatedOnChromosome |
12q24.13
|
| gptkbp:OMIM |
603349
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
Oas2
|
| gptkbp:proteinFamily |
gptkb:OAS_family
|
| gptkbp:relatedTo |
antiviral response
interferon signaling pathway |
| gptkbp:UniProtID |
P29728
|
| gptkbp:bfsParent |
gptkb:2'-5'-oligoadenylate_synthetase_family
|
| gptkbp:bfsLayer |
7
|