Nonbenzodiazepine hypnotics

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:drug
gptkbp:alsoKnownAs	gptkb:Z-drugs
gptkbp:approvedBy	gptkb:FDA
gptkbp:chemicalFormula	Non-benzodiazepine core
gptkbp:contraindication	Sleep apnea Severe liver impairment
gptkbp:developedAsAlternativeTo	gptkb:Benzodiazepines
gptkbp:discoveredIn	1990s
gptkbp:duration	Short
gptkbp:eliminationHalfLife	Varies by drug
gptkbp:example	gptkb:Zolpidem gptkb:Eszopiclone gptkb:Zaleplon gptkb:Zopiclone
gptkbp:legalStatus	Prescription only
gptkbp:marketedAs	Short-term insomnia treatment
gptkbp:mechanismOfAction	GABA-A receptor agonist
gptkbp:metabolism	Liver
gptkbp:notBenzodiazepine	true
gptkbp:onset	Rapid
gptkbp:pregnancyCategory	C (varies by drug)
gptkbp:riskFactor	Complex sleep behaviors Dependence Withdrawal symptoms
gptkbp:routeOfAdministration	gptkb:Oral
gptkbp:sideEffect	gptkb:Sleepwalking Dizziness Headache Drowsiness
gptkbp:usedFor	gptkb:Insomnia
gptkbp:bfsParent	gptkb:Insomnia
gptkbp:bfsLayer	5
https://www.w3.org/2000/01/rdf-schema#label	Nonbenzodiazepine hypnotics