Nonbenzodiazepine hypnotics

URI: https://gptkb.org/entity/Nonbenzodiazepine_hypnotics
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:alsoKnownAs gptkb:Z-drugs
gptkbp:approvedBy gptkb:FDA
gptkbp:chemicalFormula Non-benzodiazepine core
gptkbp:contraindication Sleep apnea
Severe liver impairment
gptkbp:developedAsAlternativeTo gptkb:Benzodiazepines
gptkbp:discoveredIn 1990s
gptkbp:duration Short
gptkbp:eliminationHalfLife Varies by drug
gptkbp:example gptkb:Zolpidem
gptkb:Eszopiclone
gptkb:Zaleplon
gptkb:Zopiclone
https://www.w3.org/2000/01/rdf-schema#label Nonbenzodiazepine hypnotics
gptkbp:legalStatus Prescription only
gptkbp:marketedAs Short-term insomnia treatment
gptkbp:mechanismOfAction GABA-A receptor agonist
gptkbp:metabolism Liver
gptkbp:notBenzodiazepine true
gptkbp:onset Rapid
gptkbp:pregnancyCategory C (varies by drug)
gptkbp:riskFactor Complex sleep behaviors
Dependence
Withdrawal symptoms
gptkbp:routeOfAdministration gptkb:Oral
gptkbp:sideEffect gptkb:Sleepwalking
Dizziness
Headache
Drowsiness
gptkbp:usedFor gptkb:Insomnia
gptkbp:bfsParent gptkb:Insomnia
gptkbp:bfsLayer 5