Natural killer cell large granular lymphocyte leukemia

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:disease
leukemia
gptkbp:affects gptkb:natural_killer_cells
adults
blood
gptkbp:alsoKnownAs NK-LGL leukemia
gptkbp:associatedWith gptkb:STAT3_mutation
gptkbp:diagnosedBy blood test
bone marrow biopsy
immunophenotyping
gptkbp:firstDescribed 1980s
gptkbp:frequency rare
gptkbp:hasAbnormality clonal proliferation of NK cells
https://www.w3.org/2000/01/rdf-schema#label Natural killer cell large granular lymphocyte leukemia
gptkbp:ICD-10_code C91.5
gptkbp:originatedIn natural killer cell
gptkbp:prognosis poor
gptkbp:subspecies gptkb:large_granular_lymphocyte_leukemia
gptkbp:symptom fever
splenomegaly
weight loss
night sweats
cytopenia
gptkbp:treatment chemotherapy
immunosuppressive therapy
stem cell transplant
gptkbp:bfsParent gptkb:NK-cell_LGL_Leukemia
gptkbp:bfsLayer 8