Natural killer cell large granular lymphocyte leukemia
GPTKB entity
Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:disease
leukemia |
gptkbp:affects |
gptkb:natural_killer_cells
adults blood |
gptkbp:alsoKnownAs |
NK-LGL leukemia
|
gptkbp:associatedWith |
gptkb:STAT3_mutation
|
gptkbp:diagnosedBy |
blood test
bone marrow biopsy immunophenotyping |
gptkbp:firstDescribed |
1980s
|
gptkbp:frequency |
rare
|
gptkbp:hasAbnormality |
clonal proliferation of NK cells
|
https://www.w3.org/2000/01/rdf-schema#label |
Natural killer cell large granular lymphocyte leukemia
|
gptkbp:ICD-10_code |
C91.5
|
gptkbp:originatedIn |
natural killer cell
|
gptkbp:prognosis |
poor
|
gptkbp:subspecies |
gptkb:large_granular_lymphocyte_leukemia
|
gptkbp:symptom |
fever
splenomegaly weight loss night sweats cytopenia |
gptkbp:treatment |
chemotherapy
immunosuppressive therapy stem cell transplant |
gptkbp:bfsParent |
gptkb:NK-cell_LGL_Leukemia
|
gptkbp:bfsLayer |
8
|