|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:NUMA
NuMA
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
cell division
spindle pole formation
|
|
gptkbp:biologicalProcess
|
cell cycle
chromosome segregation
mitotic spindle assembly
|
|
gptkbp:discoveredBy
|
Lydersen et al.
|
|
gptkbp:encodes
|
NuMA protein
|
|
gptkbp:Entrez_Gene_ID
|
4926
ENSG00000137497
|
|
gptkbp:expressedIn
|
ubiquitous
|
|
gptkbp:firstDescribed
|
1986
|
|
gptkbp:fullName
|
Nuclear mitotic apparatus protein 1
|
|
gptkbp:function
|
structural molecule activity
microtubule binding
mitotic spindle organization
nuclear structure maintenance
|
|
gptkbp:geneType
|
protein-coding
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NUMA1
|
|
gptkbp:interactsWith
|
gptkb:LGN
gptkb:dynein
microtubules
|
|
gptkbp:length
|
2115 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:11q13
|
|
gptkbp:location
|
gptkb:nucleus
spindle pole
nuclear matrix
|
|
gptkbp:molecularWeight
|
238 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:acute_promyelocytic_leukemia
t(11;17)(q13;q21) translocation
|
|
gptkbp:OMIM
|
164044
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Numa1
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
spindle poles
|
|
gptkbp:UniProtID
|
Q14980
|
|
gptkbp:bfsParent
|
gptkb:RARA
|
|
gptkbp:bfsLayer
|
7
|