Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
MTH2
NUDTL2 |
| gptkbp:associatedWith |
thiopurine metabolism
|
| gptkbp:discoveredIn |
2000s
|
| gptkbp:Entrez_Gene_ID |
55270
ENSG00000137804 |
| gptkbp:expressedIn |
liver
bone marrow |
| gptkbp:fullName |
nudix hydrolase 15
|
| gptkbp:function |
hydrolyzes oxidized nucleoside diphosphates
prevents incorporation of damaged nucleotides into DNA |
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
HGNC:28912
|
| https://www.w3.org/2000/01/rdf-schema#label |
NUDT15
|
| gptkbp:length |
164 amino acids
|
| gptkbp:locatedOnChromosome |
17
|
| gptkbp:location |
gptkb:17q11.2
|
| gptkbp:mutationAssociatedWith |
thiopurine toxicity
thiopurine-induced leukopenia |
| gptkbp:OMIM |
615366
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:mouse
gptkb:zebrafish |
| gptkbp:pathway |
drug metabolism
purine metabolism |
| gptkbp:PDB |
5LPG
|
| gptkbp:product |
NUDT15 protein
|
| gptkbp:relatedTo |
leukemia
pharmacogenomics inflammatory bowel disease |
| gptkbp:UniProtID |
Q9NV35
|
| gptkbp:bfsParent |
gptkb:6MBU
|
| gptkbp:bfsLayer |
7
|