Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:KLRC1
|
| gptkbp:binds |
gptkb:HLA-E
|
| gptkbp:encodedBy |
KLRC1 gene
|
| gptkbp:expressedIn |
gptkb:human
gptkb:mouse |
| gptkbp:formsHeterodimerWith |
gptkb:CD94
|
| gptkbp:foundIn |
gptkb:natural_killer_cells
some T cells |
| gptkbp:function |
inhibitory receptor
|
| gptkbp:hasITIMMotif |
true
|
| gptkbp:inhibitedBy |
activation of NK cells
|
| gptkbp:interactsWith |
CD94/NKG2A complex
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_12
|
| gptkbp:memberOf |
NKG2 family
|
| gptkbp:modulatedBy |
cytotoxicity of NK cells
|
| gptkbp:recruitedFrom |
SHP-1 phosphatase
SHP-2 phosphatase |
| gptkbp:regulates |
gptkb:immune_response
|
| gptkbp:role |
immune evasion by tumors
|
| gptkbp:structureType |
type II transmembrane protein
|
| gptkbp:target |
immunotherapy research
|
| gptkbp:UniProtID |
Q07444
|
| gptkbp:bfsParent |
gptkb:CD56bright
gptkb:CD94/NKG2 gptkb:NK_cell |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
NKG2A
|