NEIL1

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alternativeName endonuclease VIII-like 1
nei endonuclease VIII-like 1
gptkbp:associatedWith DNA repair
gptkbp:biologicalProcess DNA repair
response to oxidative stress
lyase activity
DNA glycosylase activity
gptkbp:cellularComponent gptkb:nucleus
gptkbp:discoveredBy early 2000s
gptkbp:encodes DNA glycosylase NEIL1 protein
gptkbp:Entrez_Gene_ID ENSG00000174405
79771
gptkbp:expressedIn various human tissues
gptkbp:fullName nei like DNA glycosylase 1
gptkbp:function base excision repair
removal of oxidized DNA bases
gptkbp:HGNC_ID HGNC:14076
https://www.w3.org/2000/01/rdf-schema#label NEIL1
gptkbp:locatedOnChromosome gptkb:chromosome_15
gptkbp:mutationAssociatedWith cancer susceptibility
gptkbp:OMIM 608844
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologIn E. coli Nei protein
gptkbp:proteinFamily Fpg/Nei family
gptkbp:UniProtID Q96FI4
gptkbp:bfsParent gptkb:DNA_glycosylases
gptkbp:bfsLayer 7