NDM-1 (New Delhi metallo-beta-lactamase)
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:discoveredIn |
2008
|
| gptkbp:enzyme |
metallo-beta-lactamase
|
| gptkbp:firstIsolatedFrom |
gptkb:Bacteria
gptkb:Klebsiella_pneumoniae |
| gptkbp:firstReported |
gptkb:Sweden
|
| gptkbp:foundIn |
gptkb:Enterobacteriaceae
gptkb:Pseudomonas_aeruginosa gptkb:Acinetobacter_baumannii |
| gptkbp:gene |
blaNDM-1
|
| https://www.w3.org/2000/01/rdf-schema#label |
NDM-1 (New Delhi metallo-beta-lactamase)
|
| gptkbp:inhibitedBy |
gptkb:clavulanic_acid
gptkb:EDTA |
| gptkbp:locatedOnChromosome |
plasmid
|
| gptkbp:mechanismOfAction |
hydrolyzes beta-lactam antibiotics
|
| gptkbp:namedAfter |
gptkb:New_Delhi
|
| gptkbp:publicHealthConcern |
antibiotic resistance
|
| gptkbp:resistanceProfile |
broad-spectrum beta-lactam resistance
|
| gptkbp:resistantTo |
carbapenem antibiotics
|
| gptkbp:spreadTo |
horizontal gene transfer
|
| gptkbp:threats |
critical
|
| gptkbp:bfsParent |
gptkb:Klebsiella_pneumoniae
|
| gptkbp:bfsLayer |
7
|