Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:PNGase
gptkb:peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine_amidase |
| gptkbp:associatedWith |
gptkb:NGLY1_deficiency
|
| gptkbp:biologicalProcess |
hydrolase activity
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:EC_number |
3.5.1.52
|
| gptkbp:encodedBy |
gptkb:NGLY1_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
removes N-linked glycans from glycoproteins
|
| https://www.w3.org/2000/01/rdf-schema#label |
N-glycanase 1
|
| gptkbp:involvedIn |
gptkb:ER-associated_degradation_(ERAD)
protein quality control |
| gptkbp:locatedOnChromosome |
3p24.2
|
| gptkbp:location |
cytosol
|
| gptkbp:mutationAssociatedWith |
gptkb:congenital_disorder_of_deglycosylation
|
| gptkbp:OMIM |
610661
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Drosophila_melanogaster |
| gptkbp:PDB |
6C3A
|
| gptkbp:UniProtID |
gptkb:Q96IV0
|
| gptkbp:bfsParent |
gptkb:NGLD
|
| gptkbp:bfsLayer |
6
|