Motor Neurone Disease

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instance_of gptkb:neurodegenerative_diseases
gptkbp:affects motor neurons
gptkbp:awareness_organization gptkb:Motor_Neurone_Disease_Association_(MNDA)
gptkb:ALS_Association
gptkbp:cause progressive degeneration
gptkbp:condition gptkb:frontotemporal_dementia
pain
spasticity
gptkbp:diagnosis clinical examination
nerve conduction studies
electromyography (EMG)
variable progression
average survival 3-5 years
gptkbp:epidemiology more common in men
affects 2 per 100,000 people
peak onset age 55-75
gptkbp:famous_person gptkb:Terry_Pratchett
gptkb:Stephen_Hawking
gptkb:Morrissey
gptkb:Lou_Gehrig
gptkb:David_Niven
gptkbp:genetic_studies gptkb:TARDBP
gptkb:C9orf72
gptkb:SOD1
FUS
gptkbp:historical_figures awareness campaigns
advocacy for research funding
https://www.w3.org/2000/01/rdf-schema#label Motor Neurone Disease
gptkbp:medications gptkb:Edaravone
gptkb:Riluzole
gptkbp:public_awareness gptkb:June
gptkbp:research environmental factors
genetic factors
ongoing studies
gptkbp:symptoms difficulty speaking
respiratory problems
muscle weakness
difficulty swallowing
muscle atrophy
gptkbp:treatment medications
physical therapy
supportive care
speech therapy
gptkbp:type_of Amyotrophic lateral sclerosis (ALS)
Bulbar onset ALS
Primary lateral sclerosis (PLS)
Progressive muscular atrophy (PMA)
gptkbp:bfsParent gptkb:Rob_Burrow
gptkb:Doddie_Edwards
gptkbp:bfsLayer 5