Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
motor neuron disease
neurological disorder |
| gptkbp:abbreviation |
gptkb:PLS
|
| gptkbp:affects |
adults
upper motor neurons |
| gptkbp:cause |
muscle weakness
spasticity stiffness difficulty with balance difficulty with movement |
| gptkbp:diagnosedBy |
gptkb:EMG
clinical evaluation MRI |
| gptkbp:distinctiveFeature |
gptkb:Amyotrophic_Lateral_Sclerosis
|
| gptkbp:firstDescribed |
gptkb:Jean-Martin_Charcot
|
| https://www.w3.org/2000/01/rdf-schema#label |
Primary Lateral Sclerosis
|
| gptkbp:ICD-10_code |
G12.2
|
| gptkbp:MeSH_ID |
D020521
|
| gptkbp:OMIM |
611637
|
| gptkbp:onset |
usually after age 40
|
| gptkbp:prognosis |
not usually fatal
|
| gptkbp:progression |
slow
|
| gptkbp:relatedTo |
gptkb:ALS
gptkb:hereditary_spastic_paraplegia |
| gptkbp:symptom |
dysphagia
dysarthria spastic gait |
| gptkbp:treatment |
physical therapy
medications for spasticity |
| gptkbp:bfsParent |
gptkb:PLS
gptkb:PLE |
| gptkbp:bfsLayer |
6
|