|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Mitofusin-2
HS protein
Hyperplasia suppressor gene protein
Transmembrane GTPase MFN2
|
|
gptkbp:associatedWith
|
gptkb:Charcot-Marie-Tooth_disease_type_2A
|
|
gptkbp:biologicalProcess
|
cell differentiation
cell proliferation
cell death
energy homeostasis
|
|
gptkbp:discoveredBy
|
2001
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000118579
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
gptkb:nervous_system
heart
liver
|
|
gptkbp:function
|
mitochondrial transport
mitochondrial fusion
regulation of mitochondrial morphology
mitochondrial tethering
|
|
gptkbp:gene
|
gptkb:MFN2
|
|
gptkbp:interactsWith
|
gptkb:OPA1
Mitofusin 1
|
|
gptkbp:locatedIn
|
outer mitochondrial membrane
|
|
gptkbp:locatedOnChromosome
|
gptkb:1p36.22
|
|
gptkbp:molecularWeight
|
86 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:peripheral_neuropathy
axonal degeneration
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Mfn2
|
|
gptkbp:orthologInZebrafish
|
mfn2
|
|
gptkbp:pathway
|
mitochondrial dynamics
mitophagy pathway
apoptosis pathway
|
|
gptkbp:PDB
|
6JFK
|
|
gptkbp:postTranslationalModification
|
phosphorylation
sumoylation
ubiquitination
|
|
gptkbp:RefSeq
|
NM_014874
|
|
gptkbp:regulates
|
apoptosis
mitophagy
mitochondrial metabolism
endoplasmic reticulum-mitochondria tethering
mitochondrial network architecture
|
|
gptkbp:structure
|
GTPase domain
coiled-coil domain
|
|
gptkbp:UniProtID
|
O95140
|
|
gptkbp:bfsParent
|
gptkb:MFN2
gptkb:Mfn2
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Mitofusin 2
|