Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
Rhot1
mitochondrial Rho GTPase 1 |
| gptkbp:associatedWith |
gptkb:Parkinson's_disease
|
| gptkbp:discoveredIn |
early 2000s
|
| gptkbp:domain |
GTPase domain
EF-hand motif |
| gptkbp:encodedBy |
RHOT1 gene
|
| gptkbp:function |
mitochondrial homeostasis
regulation of mitochondrial trafficking |
| https://www.w3.org/2000/01/rdf-schema#label |
Miro1
|
| gptkbp:interactsWith |
Milton/TRAK proteins
dynein motor proteins kinesin motor proteins |
| gptkbp:involvedIn |
mitochondrial transport
calcium signaling |
| gptkbp:location |
outer mitochondrial membrane
|
| gptkbp:molecularWeight |
~70 kDa
|
| gptkbp:mutationAssociatedWith |
neurodegeneration
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
Drosophila melanogaster (Miro)
|
| gptkbp:regulates |
mitochondrial movement along microtubules
|
| gptkbp:UniProtID |
Q8IXI2
|
| gptkbp:bfsParent |
gptkb:PARK2_gene
|
| gptkbp:bfsLayer |
7
|