Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:Cyclic_peptide_toxin
|
| gptkbp:associatedWith |
Harmful algal blooms
|
| gptkbp:bioaccumulatesIn |
Aquatic organisms
|
| gptkbp:chemicalFormula |
C49H74N10O12 (for Microcystin-LR)
|
| gptkbp:class |
Hepatotoxin
Cyanotoxin |
| gptkbp:degradedBy |
Ozone
UV light Certain bacteria |
| gptkbp:detects |
gptkb:ELISA
gptkb:HPLC LC-MS/MS |
| gptkbp:environmentalImpact |
Eutrophication
|
| gptkbp:firstDescribed |
1977
|
| gptkbp:firstIsolatedFrom |
Microcystis aeruginosa
|
| gptkbp:foundIn |
Freshwater
|
| gptkbp:hasVariant |
Over 100
|
| gptkbp:IUPACName |
(for Microcystin-LR) cyclo-(D-Ala-L-Leu-D-MeAsp-L-Arg-Adda-D-Glu-Mdha)
|
| gptkbp:mechanismOfAction |
Inhibition of protein phosphatases 1 and 2A
|
| gptkbp:molecularWeight |
Approximately 995 Da (for Microcystin-LR)
|
| gptkbp:monitors |
Environmental agencies
|
| gptkbp:mostCommonVariant |
Microcystin-LR
|
| gptkbp:namedAfter |
Microcystis genus
|
| gptkbp:notRemovedBy |
Boiling
Conventional water treatment |
| gptkbp:potentialCarcinogen |
Yes
|
| gptkbp:potentialExposureRoute |
Drinking water
Food chain Recreational water |
| gptkbp:producedBy |
gptkb:Bacteria
|
| gptkbp:regulates |
gptkb:World_Health_Organization
Drinking water guidelines |
| gptkbp:removes |
Activated carbon filtration
Advanced oxidation processes |
| gptkbp:riskFactor |
gptkb:Humans
gptkb:livestock gptkb:Wildlife |
| gptkbp:stableUnder |
gptkb:Heat
Light |
| gptkbp:structureContains |
Adda amino acid
|
| gptkbp:symptomsOfExposure |
Vomiting
Jaundice Diarrhea Abdominal pain Liver damage Gastrointestinal symptoms Death (in severe cases) |
| gptkbp:toxicity |
Liver
|
| gptkbp:WHOguidelineValue |
1 µg/L in drinking water
|
| https://www.w3.org/2000/01/rdf-schema#label |
Microcystins
|