Microcystins

GPTKB entity

Statements (52)
Predicate Object
gptkbp:instanceOf Cyclic peptide toxin
gptkbp:associatedWith Harmful algal blooms
gptkbp:bioaccumulatesIn Aquatic organisms
gptkbp:chemicalFormula C49H74N10O12 (for Microcystin-LR)
gptkbp:class Hepatotoxin
Cyanotoxin
gptkbp:degradedBy Ozone
UV light
Certain bacteria
gptkbp:detects gptkb:ELISA
gptkb:HPLC
LC-MS/MS
gptkbp:environmentalImpact Eutrophication
gptkbp:firstDescribed 1977
gptkbp:firstIsolatedFrom Microcystis aeruginosa
gptkbp:foundIn Freshwater
gptkbp:hasVariant Over 100
https://www.w3.org/2000/01/rdf-schema#label Microcystins
gptkbp:IUPACName (for Microcystin-LR) cyclo-(D-Ala-L-Leu-D-MeAsp-L-Arg-Adda-D-Glu-Mdha)
gptkbp:mechanismOfAction Inhibition of protein phosphatases 1 and 2A
gptkbp:molecularWeight Approximately 995 Da (for Microcystin-LR)
gptkbp:monitors Environmental agencies
gptkbp:mostCommonVariant Microcystin-LR
gptkbp:namedAfter Microcystis genus
gptkbp:notRemovedBy Boiling
Conventional water treatment
gptkbp:potentialCarcinogen Yes
gptkbp:potentialExposureRoute Drinking water
Food chain
Recreational water
gptkbp:producedBy gptkb:Bacteria
gptkbp:regulates gptkb:World_Health_Organization
Drinking water guidelines
gptkbp:removes Activated carbon filtration
Advanced oxidation processes
gptkbp:riskFactor gptkb:Humans
gptkb:livestock
gptkb:Wildlife
gptkbp:stableUnder gptkb:Heat
Light
gptkbp:structureContains Adda amino acid
gptkbp:symptomsOfExposure Vomiting
Jaundice
Diarrhea
Abdominal pain
Liver damage
Gastrointestinal symptoms
Death (in severe cases)
gptkbp:toxicity Liver
gptkbp:WHOguidelineValue 1 µg/L in drinking water
gptkbp:bfsParent gptkb:Blue-green_algae
gptkbp:bfsLayer 5