Mianserin

URI: https://gptkb.org/entity/Mianserin

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:antidepressant gptkb:chemical_compound
gptkbp:approvedBy	gptkb:Australia gptkb:New_Zealand gptkb:United_Kingdom 1970s
gptkbp:ATCCode	N06AX03
gptkbp:brand	gptkb:Tolvon gptkb:Norval
gptkbp:CASNumber	24219-97-4
gptkbp:chemicalFormula	C18H20N2
gptkbp:compatibleWith	gptkb:United_States
gptkbp:contraindication	gptkb:liver_disease mania history of agranulocytosis
gptkbp:discoveredBy	gptkb:Organon
gptkbp:eliminationHalfLife	21-61 hours
gptkbp:excretion	urine feces
gptkbp:hasInChIKey	VZJTYGJNQZHZMA-UHFFFAOYSA-N
gptkbp:hasSMILES	CN1CC2=CC=CC=C2C3=CC=CC=C3N=C1CN4CCCCC4
gptkbp:IUPACName	(2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine
gptkbp:KEGGID	D08207
gptkbp:legalStatus	prescription only
gptkbp:mechanismOfAction	gptkb:norepinephrine_reuptake_inhibitor gptkb:antihistamine gptkb:serotonin_receptor_antagonist
gptkbp:metabolism	liver
gptkbp:molecularWeight	264.37 g/mol
gptkbp:pregnancyCategory	gptkb:C_(Australia)
gptkbp:PubChem_CID	gptkb:CHEMBL1426 4166 4023 DB06148
gptkbp:routeOfAdministration	oral
gptkbp:sideEffect	constipation weight gain drowsiness dry mouth agranulocytosis
gptkbp:synonym	gptkb:Mianserinum gptkb:Org_GB_94
gptkbp:UNII	7RH2S63I3E
gptkbp:usedFor	gptkb:major_depressive_disorder insomnia anxiety disorders
gptkbp:bfsParent	gptkb:Antidepressants
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	Mianserin