Statements (45)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:blockade
|
| gptkbp:brand |
gptkb:Astra_Zeneca
gptkb:Toprol-XL |
| gptkbp:category |
gptkb:C
|
| gptkbp:chemical_formula |
C15 H25 NO3
|
| gptkbp:class |
selective beta-1 adrenergic antagonist
aryloxypropanolamine |
| gptkbp:contraindication |
gptkb:asthma
heart block severe bradycardia |
| gptkbp:dosage_form |
200 mg once daily
100 mg once daily 400 mg once daily 50 mg once daily |
| gptkbp:excretion |
urine
|
| gptkbp:form |
extended-release tablet
solution for injection |
| gptkbp:formulation |
sustained-release
immediate-release |
| gptkbp:healthcare |
gptkb:1992
|
| https://www.w3.org/2000/01/rdf-schema#label |
Metoprolol Succinate
|
| gptkbp:indication |
anxiety
thyrotoxicosis post-myocardial infarction migraine prophylaxis |
| gptkbp:interacts_with |
gptkb:digoxin
MAO inhibitors calcium channel blockers |
| gptkbp:lifespan |
3 to 7 hours
|
| gptkbp:metabolism |
liver
|
| gptkbp:route_of_administration |
oral
intravenous |
| gptkbp:side_effect |
gptkb:depression
dizziness fatigue bradycardia |
| gptkbp:trade |
gptkb:Betaloc
gptkb:Lopressor |
| gptkbp:used_for |
hypertension
heart failure arrhythmias angina pectoris |
| gptkbp:weight |
265.37 g/mol
|
| gptkbp:bfsParent |
gptkb:metoprolol
|
| gptkbp:bfsLayer |
5
|