|
gptkbp:instance_of
|
gptkb:pharmaceuticals
|
|
gptkbp:approves
|
gptkb:FDA
|
|
gptkbp:atccode
|
C07 AB02
|
|
gptkbp:brand
|
gptkb:Toprol-XL
|
|
gptkbp:category
|
gptkb:unknown
Category C
|
|
gptkbp:class
|
gptkb:blockade
|
|
gptkbp:clinical_trial
|
Phase IV
|
|
gptkbp:contraindication
|
gptkb:asthma
heart block
severe bradycardia
|
|
gptkbp:dosage_form
|
100 mg
50 mg
extended-release tablet
25 mg
immediate-release tablet
|
|
gptkbp:effective_date
|
gptkb:1992
|
|
gptkbp:formulation
|
gptkb:tablet
injection
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Lopressor
|
|
gptkbp:ingredients
|
gptkb:metoprolol
|
|
gptkbp:interacts_with
|
gptkb:digoxin
MAO inhibitors
calcium channel blockers
antidiabetic medications
|
|
gptkbp:legal_status
|
prescription only
|
|
gptkbp:lifespan
|
3 to 7 hours
|
|
gptkbp:manufacturer
|
gptkb:Astra_Zeneca
|
|
gptkbp:marketed_as
|
metoprolol succinate
metoprolol tartrate
|
|
gptkbp:patient_population
|
gptkb:children
adults
|
|
gptkbp:provides_guidance_on
|
gptkb:American_Heart_Association
gptkb:European_Society_of_Cardiology
gptkb:American_College_of_Cardiology
|
|
gptkbp:rounds
|
hepatic
renal
|
|
gptkbp:route_of_administration
|
oral
intravenous
|
|
gptkbp:side_effect
|
gptkb:depression
dizziness
fatigue
nausea
bradycardia
|
|
gptkbp:used_for
|
gptkb:organ
hypertension
heart attack prevention
|
|
gptkbp:bfsParent
|
gptkb:metoprolol
|
|
gptkbp:bfsLayer
|
5
|