Statements (66)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:bfsLayer |
3
|
| gptkbp:bfsParent |
gptkb:item
|
| gptkbp:associated_with |
vascular calcification
|
| gptkbp:code |
gptkb:MGP_gene
|
| gptkbp:discovered_by |
gptkb:mythological_figure
|
| gptkbp:established |
calcification of soft tissues
|
| gptkbp:function |
regulates bone mineralization
|
| gptkbp:has_impact_on |
osteoclast activity
|
| gptkbp:has_role |
development of the cardiovascular system
|
| https://www.w3.org/2000/01/rdf-schema#label |
Matrix Gla-protein
|
| gptkbp:interacts_with |
gptkb:bone_morphogenetic_proteins
|
| gptkbp:is_associated_with |
age-related diseases
metabolic disorders chronic diseases chronic pain metabolic syndrome fibrosis tumor progression |
| gptkbp:is_found_in |
blood vessels
cartilage matrix |
| gptkbp:is_involved_in |
cell differentiation
cell proliferation metabolic pathways wound healing immune responses cell signaling pathways cell survival inflammatory responses angiogenesis vascular remodeling tissue repair cell adhesion cell migration tissue homeostasis cellular stress responses mineral homeostasis calcification processes regulation of cardiovascular health |
| gptkbp:is_linked_to |
gptkb:psychologist
autoimmune diseases chronic stress chronic kidney disease vascular diseases atherosclerosis chronic inflammation diabetes complications neoplastic processes |
| gptkbp:is_part_of |
extracellular vesicles
mineralized tissues |
| gptkbp:is_represented_in |
cartilage
endothelial cells muscle tissues smooth muscle cells placental tissues lung tissues adipose tissues kidney tissues |
| gptkbp:is_studied_in |
cardiovascular disease research
osteoporosis research |
| gptkbp:location |
extracellular matrix
|
| gptkbp:produced_by |
osteoblasts
|
| gptkbp:promoter |
MGP
|
| gptkbp:regulates |
gptkb:calcitriol
hormones |
| gptkbp:requires |
vitamin K for activation
|