Mannose-6-phosphate receptor

GPTKB entity

Statements (26)
Predicate Object
gptkbp:instanceOf gptkb:receptor_tyrosine_kinase
gptkb:protein
gptkbp:alternativeName gptkb:IGF2R
insulin-like growth factor 2 receptor
M6PR
gptkbp:binds gptkb:mannose-6-phosphate
gptkbp:discoveredBy Stuart Kornfeld
gptkbp:foundIn gptkb:Golgi_apparatus
gptkb:plasma_membrane
endosomes
lysosomes
gptkbp:function lysosomal enzyme targeting
gptkbp:gene gptkb:IGF2R
M6PR
gptkbp:hasIsoform cation-dependent mannose-6-phosphate receptor
cation-independent mannose-6-phosphate receptor
https://www.w3.org/2000/01/rdf-schema#label Mannose-6-phosphate receptor
gptkbp:involvedIn protein sorting
lysosomal biogenesis
gptkbp:molecularWeight approximately 300 kDa (cation-independent)
approximately 46 kDa (cation-dependent)
gptkbp:relatedTo lysosomal storage diseases
gptkbp:species gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkbp:bfsParent gptkb:Lysosome
gptkbp:bfsLayer 6