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gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:MYF3
gptkb:bHLHc1
MYOD
|
|
gptkbp:associatedWith
|
gptkb:rhabdomyosarcoma
|
|
gptkbp:discoveredBy
|
gptkb:Andrew_B._Lassar
Harold M. Weintraub
|
|
gptkbp:discoveredIn
|
1987
|
|
gptkbp:encodes
|
Myogenic factor MyoD
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000129152
4654
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
|
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gptkbp:fullName
|
gptkb:myogenic_differentiation_1
|
|
gptkbp:function
|
transcription factor activity
regulation of muscle differentiation
|
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gptkbp:geneType
|
protein-coding
|
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gptkbp:HGNC_ID
|
gptkb:HGNC:7611
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
MYOD1 gene
|
|
gptkbp:interactsWith
|
gptkb:ID_proteins
gptkb:E_proteins
|
|
gptkbp:length
|
318 amino acids
3 exons
|
|
gptkbp:locatedOnChromosome
|
gptkb:11p15.1
11
|
|
gptkbp:mRNA_length
|
~1.6 kb
|
|
gptkbp:mutationAssociatedWith
|
can cause muscle cancer
|
|
gptkbp:OMIM
|
159970
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
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gptkbp:orthologInMouse
|
gptkb:Myod1
|
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gptkbp:pathway
|
myogenesis
muscle cell differentiation
|
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gptkbp:proteinFamily
|
basic helix-loop-helix (bHLH) transcription factors
|
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gptkbp:regulates
|
muscle atrophy
muscle repair
muscle hypertrophy
cell cycle exit in myoblasts
muscle fiber type specification
muscle regeneration
muscle-specific gene expression
muscle satellite cell differentiation
muscle stem cell activation
myoblast fusion
myogenic lineage commitment
|
|
gptkbp:regulatoryElement
|
E-box DNA motif
|
|
gptkbp:symbol
|
gptkb:MYOD1
|
|
gptkbp:transcriptionalActivator
|
muscle-specific genes
|
|
gptkbp:UniProtID
|
gptkb:P15172
|
|
gptkbp:bfsParent
|
gptkb:MyoD
gptkb:myoblast_determination_protein_1
|
|
gptkbp:bfsLayer
|
7
|