MSH2 gene mutation

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instance_of gptkb:Genetics
gptkbp:affects treatment options
DNA mismatch repair
gptkbp:can_detect genetic testing
gptkbp:can_increase_risk_for other cancers
gptkbp:can_lead_to gptkb:Oncology
endometrial cancer
prophylactic surgeries
gptkbp:can_result_in microsatellite instability
gptkbp:caused_by somatic mutations
inherited variants
gptkbp:has_a_focus_on genetic counseling
https://www.w3.org/2000/01/rdf-schema#label MSH2 gene mutation
gptkbp:inherits_from autosomal dominant manner
gptkbp:is_associated_with gptkb:Lynch_syndrome
increased surveillance recommendations
gptkbp:is_essential_for cancer risk assessment
gptkbp:is_involved_in repairing DNA errors
gptkbp:is_linked_to tumor development
gptkbp:is_located_in chromosome 2
gptkbp:is_monitored_by clinical trials
gptkbp:is_part_of gptkb:hereditary_nonpolyposis_colorectal_cancer_(HNPCC)
mismatch repair system
gptkbp:is_recognized_by biopsy samples
gptkbp:is_related_to family history of cancer
gptkbp:is_studied_in cancer genetics
gptkbp:type_of gptkb:Genetics
gptkbp:bfsParent gptkb:Lynch_syndrome
gptkbp:bfsLayer 6